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Genetics to Treatment: Leaders Speak
about Research Findings and Implications
March 13, 2010
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Richmond, VA
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Conference Sponsors
The National Education Alliance for
Borderline Personality Disorder
Department of Psychiatry, Virginia
commonwealth University (VCU)
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Time and
Location
8:00 a.m. – 4:00 p.m.
Hermes A. Kontos Medical Sciences
Building
1217 E. Marshall St., Richmond, VA
For information on continuing
education and special needs, contact
conference registrar at
conferences@neabpd.org
Statement of Need
Since 2002, NEA-BPD has sponsored or
collaborated in presenting 35
conferences and evaluations confirm
the need for professional and
general education to understand
diagnostic issues and potential
treatments for this disorder. Recent
studies indicate a higher lifetime
prevalence (5.9%) than previously
thought, thus emphasizing the need
to disseminate information and
encourage dialogue on this disorder.
NEA-BPD has been awarded two NIMH
grants to further this mission of
translating research to make
information available to clinicians
and the public.
Assumptions- Diagnosis and treatment
interventions of borderline
personality disorder should begin as
soon as possible
- Borderline
Personality disorder (BPD) is a
severe and generally chronic
disorder and people who suffer from
it are underserved.
- Friends and families are often
bewildered and do not know how to
help.
- Treatment programs for those with
BPD need to be more readily
available.
- Families need access to programs
such as those already developed for
several other mental illnesses.
- BPD presents patients, their
families, clinicians, and
researchers with multiple
challenges.
- BPD frequently co-occurs with SUD,
confounding all of the above
challenges
Purpose
Research on BPD has lagged behind
that of other major disorders. This
program will address the impact of
genetic research and its impact on
current understandings and practice
in the treatment of BPD and best
practice in current treatment
options on the complex challenges
associated with the diagnosis and
treatment of BPD in order to inform
clinicians, mental health
professionals, families and
consumers.
Audience
This conference will provide a forum
for professionals, family members,
and consumers to better understand
the disorder from various
perspectives.
The Conference is for physicians,
psychiatrists, psychologists, social
workers, family therapists,
counselors, nurses, emergency room
personnel, law enforcement personnel
and agencies, educators, family
members, friends, and consumers.
Medical and mental health students
are particularly encouraged to
attend.
Accreditation and Credit Statement
University Health Services
Professional Education Programs
(UHS-PEP) of Virginia Commonwealth
University Health System is
accredited by the Accreditation
Council for Continuing Medical
Education to provide continuing
medical education for physicians.
UHS-PEP designates this educational
activity for a maximum of 6
AMA PRA Category 1 Creditsä.
Physicians should only claim credit
commensurate with the extent of
their participation in the activity.
This continuing education activity
meets the criteria of Virginia
Commonwealth University and the
Southern Association of Colleges and
Schools. .6 CEUs will be awarded and
recorded with the University.
Virginia Commonwealth University is
an equal opportunity/affirmative
action employer.
Course Description
Research findings are shaping and
will continue to reshape a more
accurate reflection of the structure
and nature of underlying factors in
psychiatric disorders. As with other
disorders, the research findings
impact many aspects of borderline
personality disorder including leads
to clinical advances in treatments,
the reduction of personal and
community burdens, and the suffering
that psychiatric disorders too often
inflict.
Presenters will offer current
information on research and best
practice relating to BPD. Each
session allows time for questions
and answers, and the program
includes an interactive panel that
will discuss emerging issues of
understanding the disorder and
developing treatments, and the
dissemination of current information
on BPD.
Conference Focus
Points
This conference is for clinical and
mental health professionals, and
open to consumers, and family
members. This program will provide a
forum for professionals, family
members, and consumers to better
understand BPD from various
perspectives. Presenters will offer
current information on research and
best practice relating to BPD, Each
session allows time for questions
and answers, and the day will close
with an interactive panel discussion
that will discuss emerging issues of
understanding the disorder,
developing treatments, and
disseminating current information on
BPD.
This conference on research in genetics and
the implications and impact of research
findings on treatment, with a focus on
borderline personality disorder, will
address topics such as:- identify the current paradigms in psychiatric genetics
- list the core symptoms of borderline personality disorder
- describe the primary treatment focuses
- explain the biological factors and associated molecular neuropharmacological principles
related to BPD
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COURSE DIRECTORS
Perry D. Hoffman, PhD
President, National Education
Alliance for Borderline Personality
Disorder
Joel J. Silverman, MD
James Asa Shield, Jr., M.D.
Professor and Chairman, Department
of Psychiatry, School of Medicine,
Virginia Commonwealth University
CONFERENCE COORDINATORS
Rupa Murthy
Trish Woodward
CONFERENCE REGISTRAR
Trish Woodward, MAT
Secretary, National Education
Alliance for Borderline Personality
Disorder
FACULTY PRESENTERS
Robert O. Friedel, MD
Distinguished Clinical Professor of
Psychiatry, Virginia Commonwealth
University
Professor Emeritus, University of
Alabama at Birmingham.
John G. Gunderson, MD
Professor of Psychiatry, Harvard
Medical School
Director, Center for Treatment and
Research on BPD, Mclean Hospital,
Belmont, MA
Kenneth S. Kendler, MD
Rachel Brown Banks Distinguished
Professor of Psychiatry;
Professor of Human Genetics
Director, Psychiatric Genetics
Research Program;
Director, Virginia Institute for
Psychiatric and Behavioral Genetics
Virginia Commonwealth University
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PROGRAM
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Printable Program
Genetics to Treatment:
Leaders Speak about Research
Findings and Implications
Saturday. March 13, 2009 · Richmond,
Virginia
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| 8:00 am |
Registration and Coffee |
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| 8:30 am |
Welcome and Opening Remarks:
Joel J. Silverman, MD, Professor and
Chairman, Department of Psychiatry
Perry D. Hoffman, PhD, President,
NEA-BPD |
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| 9:00 am |
Psychiatric Genetics: An
overview and focus on Borderline
Personality Disorder
Kenneth S. Kendler, MD
Rachel Brown Banks Distinguished
Professor of Psychiatry; Professor
of Human Genetics
Director, Psychiatric Genetics
Research Program; Director, Virginia
Institute for Psychiatric and
Behavioral Genetics
Objectives:
1. To understand the current
paradigms used in psychiatric
genetics -- genetic epidemiology and
gene-finding methods -- and their
relative strengths and weaknesses
2. To understand how multivariate
genetic analyses can clarify the
origins of patterns of comorbidity
in psychiatric illness and review
the current results obtained by
applying these methods.
3. To understand current research on
the genetics of personality
disorders and particularly
borderline personality disorder. |
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| 10:30 am |
Break |
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| 10:45 am |
Development of BPD:
phenotypes, mentalization, trauma,
and unshared environment
John G. Gunderson, MD
Professor of Psychiatry, Harvard
Medical School
Director, Center for Treatment and
Research on BPD, Mclean Hospital,
Belmont, MA
Objectives:
1. identify temperamental
structures, interpersonal
interactions, and significant events
that modify expressions of the genes
that predispose to BPD
2. understand the strength and
limitations of mentalization as a
way to understand BPD's core
psychopathology |
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| 11:45 pm |
Lunch |
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| 12:45 pm |
Psychosocial Treatment of
BPD: stigma, comorbidity, and the
basic components of psychotherapy
John G. Gunderson, MD
Objectives:
1. learn how and why to disclose the
BPD diagnosis to patients and
families
2. learn why BPD should be the
primary treatment focus when
co-occurring with bipolar disorder
or MDD, but not when co-occurring
with substance abuse or antisocial
personality disorder |
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| 1:45 pm |
Panel discussion
Discussants: Drs. Friedel,
Gunderson, Kendler |
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| 2:45 pm |
Break |
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| 3:00 pm |
The Treatment of BPD with
Medications: A neuropharmacologically-based
approach
Robert O. Friedel, MD
Distinguished Clinical Professor of
Psychiatry, Virginia Commonwealth
University
Professor Emeritus,
University of Alabama at
Birmingham
Objectives
1. Participants will understand the
four diagnostic dimensions/domains
of BPD, and the frequently
co-occurring disorders associated
with BPD.
2. Participants will understand how
to distinguish the core symptoms of
BPD from the overlapping symptoms of
the co-occurring disorders.
3. Participants will understand the
rationale and the strategies for
utilizing medications for the
treatment of BPD and any
co-occurring disorders.
4. Participants will understand the
fundamental biological factors that
increase the risk of developing BPD,
and the associated molecular
psychopharmacological principles
that enhance the proper use of
medications for patients with BPD.
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| 4:00 pm |
Closing Remarks and Adjourn |
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CONFERENCE FACULTY BIOS
John G. Gunderson, MD
Dr. John Gunderson is a Professor of
Psychiatry at Harvard Medical
School. At McLean Hospital he is
Director of the Borderline Center's
clinical, training, and research
program. His seminal studies on the
diagnosis, families, psychodynamics,
treatment and pathogenesis of
borderline personality disorder
helped transform the diagnosis from
a psychoanalytic construct into an
empirically validated and
internationally recognized disorder
and earned him recognition as the
"father" of this disorder. He has
increased awareness of the burdens
for families and championed the
involvement as collaborators. He
chaired the DSM IV work group on
personality disorders, and currently
leads two major NIMH-funded studies,
one on the longitudinal stability
and the other on family transmission
of borderline personality disorder
In 2009 McLean Hospital honored his
contributions by establishing a new
treatment center in Cambridge, Mass
called the Gunderson Residence. He
remains actively involved in
treating borderline patients using
all modalities and brings this
experience to bear in his talks and
writing.
Robert O. Friedel, MD
Dr. Friedel is Distinguished
Clinical Professor of Psychiatry at
Virginia Commonwealth University,
and Professor Emeritus at the
University of Alabama at Birmingham.
He received his undergraduate and
medical degrees from Duke
University, and completed an
internship in internal medicine and
a residency in psychiatry at Duke.
He served for two years as a
research fellow at the National
Institute of Mental Health in
Bethesda, Maryland.
Previously, Dr. Friedel was Heman E.
Drummond Professor and Chair of the
Department of Psychiatry and
Behavioral Neurobiology at the
University of Alabama at Birmingham.
He has also served as chair of the
departments of psychiatry at
Virginia Commonwealth University and
the University of Michigan, and
Executive Director of the Mental
Health Research Institute at the
University of Michigan. Dr. Friedel
has worked in the private sector as
Senior Vice President,
Physician-in-Chief, Director of
Research and as a member of the
Board of Directors of Charter
Medical Corporation.
Dr. Friedel's research interests
have focused, in part, on developing
effective pharmacological treatments
for patients with borderline
personality disorder, and on
identifying biological defects in
patients with this disorder. He has
founded Borderline Personality
Disorder Clinics at UAB and at
MCV/VCU, and now directs the MCV/VCU
Clinic. In 2004, Dr. Friedel
published a book for patients with
borderline disorder, their families
and mental health professionals
titled Borderline Personality
Disorder Demystified.
Dr. Friedel serves on the Scientific
Advisory Board of the National
Education Alliance for Borderline
Personality Disorder, and was named
a Psychiatrist of the Year in 2007
by the National Alliance on Mental
Illness (NAMI). He is
co-editor-in-chief of Current
Psychiatry Reports, and is on the
editorial board of the Journal of
Clinical Psychopharmacology. He is a
member of Alpha Omega Alpha Honor
Medical Society and a number of
other professional and scientific
organizations. Dr. Friedel has
published over 100 scientific
articles, book chapters and books,
and is listed in Who's Who in
Medicine and Healthcare and in Who's
Who in America.
Kenneth S. Kendler, MD
Kenneth S. Kendler, Banks
Distinguished Professor of
Psychiatry, Professor of Human
Genetics, Medical College of
Virginia, Virginia Commonwealth
University.
Dr. Kendler received his medical and
psychiatric training at Stanford and
Yale University, respectively. Since
1983, he has been engaged in studies
of the genetics of psychiatric and
substance use disorders, including
schizophrenia, major depression,
alcoholism, personality disorders
and nicotine dependence. He has
utilized methods ranging from family
studies, to large-sample
population-based twin studies to
molecular genetic studies aimed at
identifying specific genes that
influence the vulnerability to
schizophrenia, alcoholism,
depression and nicotine dependence.
Data collection for these studies
has been completed in Virginia,
Ireland, China, Norway and Sweden.
He has published over 550 reviewed
journals, has received a number of
national and international awards
for his work and serves on several
Editorial Boards and is Editor of
Psychological Medicine. Since 1996,
he has served as Director of the
Virginia Institute of Psychiatric
and Behavioral Genetics.
COURSE DIRECTORS
Perry D. Hoffman, PhD
Perry D. Hoffman, Ph.D. is the
President and a co-founder of the
National Education Alliance for
Borderline Personality Disorder
(NEA-BPD). She has several grants
from the National Institute of
Mental Health with a focus on
families who have a relative with
borderline personality disorder. Dr.
Hoffman is co-designer of the
12-week psycho-education course for
families, Family Connections, which
is available in many locations both
in the United States as well as
other countries. She is a co editor,
with John G. Gunderson, MD, of the
book Understanding and Treating
Borderline Personality Disorder: A
Guide for Professionals and Family
Member and co editor of Borderline
Personality Disorder: Meeting the
Challenges to Successful Treatment.
Dr. Hoffman, who is intensively
trained in Dialectical Behavior
Therapy (DBT), has been the director
of several treatment programs in the
New York area and now is in private
practice in New York City and
Westchester County, NY.
Joel J. Silverman, MD
Dr. Silverman is the James A. Shield
Jr., MD, Professor of Psychiatry and
Chair of the Department of
Psychiatry at the Medical College of
Virginia at VCU in Richmond,
Virginia. He has chaired this
department since 1984. Born in
Battle Creek, Michigan, he received
his BA degree from Washington
University in St. Louis, Missouri,
in 1965, and his MD degree from
University of Kansas Medical School
in Kansas City, Missouri, in 1969.
He completed a straight medicine
internship in Chicago. He then
performed psychiatric residency
training at University of Kansas
School of Medicine and was a Senior
Resident and Fellow at Medical
College of Virginia. Following
residency training, Dr. Silverman
was the Chief of Psychiatric Service
at the U.S. Army Hospital, Camp
Zama, Japan, from 1973-1975. Upon
his return, he joined the faculty at
the Medical College of Virginia.
Dr. Silverman serves on several
American Psychiatric Association
components including serving as Vice
Chair of the Council on Medical
Education and Lifelong Learning, and
was a member of the Council on
Advocacy and Public Policy. He
serves as a consultant to the APA
Scientific Program Committee. He
served on the Committee on Public
Funding for Psychiatric Services,
served on the Consortium on Funding
of the Council on Psychiatric
Services, and served as Chair of the
APA Corresponding Committee on
Physician Health, Illness &
Impairment. He was also a member of
the Public Affairs Committee of the
National Depressive/Manic Depressive
Association, the Finance Committee
of the Academy of Psychosomatic
Medicine, and is a member of the VCU
Health System Finance and Property
Committee and the Board of MCV
Physicians. In 1990, Dr. Silverman
received the Distinguished Service
Award from the APA District Branch,
the Psychiatric Society of Virginia.
Dr. Silverman has received numerous
honors and awards. He was the
President of the American
Association of Chairs of Departments
of Psychiatry and was Chair of the
Residency Review Committee in
Psychiatry of the Accreditation
Council of Graduate Medical
Education.
Virginians for Mental Health
Advocacy is a multidisciplinary
advocacy group that Dr. Silverman
founded in 1988. This organization
wrote Virginia parity legislation
and has been active in protecting
the rights of citizens with mental
illness. He has been a senior
examiner for the American Board of
Psychiatry and Neurology for many
years.
In the area of research, Dr.
Silverman has played an important
role, building a strong research
department. An Institute of Medicine
psychiatry study chose to review the
department as part of its study of
departments that have built credible
research programs.
Dr. Silverman regularly teaches
medical students and almost yearly
receives medical student teaching
awards. He has built a strong
residency training and medical
student education program, and in
1975 founded the VCU/MCV division of
Consultation/Liaison. In 2000, he
was a School of Medicine nominee for
VCU Distinguished Service Award. In
1999, he was named Fellow of the
American College of Psychiatrists.
In 1997, he was awarded the American
Psychiatric Association Nancy G. A.
Roeske Certificate of Recognition in
Medical Student Education and is a
Fellow of the American Psychiatric
Association. He has been recognized
in Best Doctors in America for many
years.
Dr. Silverman was the Assistant
Editor of Psychosomatics from 1986
to 1995 and has been a reviewer for
American Journal of Psychiatry,
Psychosomatics, Archives of General
Psychiatry, and Journal of American
Medical Association.
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LODGING
HOTEL GROUP CODE: BEABP2
Hilton Garden Inn
Richmond Downtown
501 East Broad Street, Richmond,
Virginia 23219
804-344-4300
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PARKING
The Hermes A. Kontos Medical
Sciences Building is located on the
medical campus of Virginia
Commonwealth University at 1217 East
Marshall Street in Richmond,
Virginia.
Parking is available nearby at some
of the following places:
On-street parking – metered spaces,
generally free on weekends and after
5:00 pm weekdays
8th Street Deck: 8th and Duvall
Parking lot at 10th St. between Clay
and Marshall
Parking lot at 11th and Broad Sts.
Parking lots north of the Richmond
Coliseum accessible from 5th or 7th
Sts.
Parking lots at Jackson and 7th
accessible from 7th or Duval Sts.
Coliseum Parking Deck, 7th St.
across from the Richmond Coliseum
Note: persons attempting to park in
the “Patients and Visitors” parking
deck may be turned away as this deck
is restricted to patients of and
visitors to the medical facilities.
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