Research

Do You Cut or Hurt Yourself on Purpose?

Researchers at the New York State Psychiatric Institute in New York City are conducting a study of an investigational, minimal risk, non-invasive treatment called Transcranial Direct Current Stimulation (tDCS), as a form of therapy for people who hurt themselves.

If you cut or hurt yourself, are between the ages of 18-60 and are interested in participating in a research study involving assessments of your mood and behavior, brain imaging, and tDCS, please contact Damaris Fuster at fusterd@nyspi.columbia.edu or 646-774-7561.

More information is also available at tdcs research

Opportunity to Participate in Research!

At the Mood and Personality Research Group in New York City, we are dedicated to learning more about the causes of and better treatments for Borderline Personality Disorder. We are one of the first groups to study the biology underlying personality difficulties.

If interested, you may be eligible to participate in a study at the Icahn School of Medicine at Mount Sinai in New York City. You must be between 18 and 55 years old and medically healthy.

Reimbursement is provided, and travel fare for some studies may be provided in the form of a Metrocard.
For more information please visit our Facebook page at moodandpd, Mount Sinai website at mood and personality disorders research program , or call 212-241-9775.

*Please note that all study procedures take place in New York City. If you live outside of the New York City area or do not plan to travel to New York City to stay for at least 2 months, you will not be eligible for this program.

Research on Borderline Personality Disorder

Some research suggests that brain areas involved in emotional responses become overactive in people with BPD when they perform tasks that they see as negative. 1  People with the disorder also show less activity in areas of the brain that help control emotions and aggressive impulses and allow people to understand the context of a situation. These findings may help explain the unstable and sometimes explosive moods seen in BPD.2

Another study showed that, when looking at emotionally negative pictures, people with BPD used different areas of the brain than people without the disorder. Those with the illness tended to use brain areas related to reflexive actions and alertness, which may explain the tendency to act impulsively on emotional cues. 3

1. Kernberg OF, Michels R. Borderline personality disorder. Am J Psychiatry. 2009 May; 166(5): 505–8.

2. Lis E, Greenfield B, Henry M, Guile JM, Dougherty G. Neuroimaging and genetics of borderline personality disorder: a review. J Psychiatry Neurosci. 2007 May; 32(3): 162–73; Silbersweig D, Clarkin JF, Goldstein M, Kernberg OF, Tuescher O, Levy KN, Brendel G, Pan H, Beutel M, Pavony MT, Epstein J, Lenzenweger MF, Thomas KM, Posner MI, Stern E. Failure of frontolimbic inhibitory function in the context of negative emotion in borderline personality disorder. Am J Psychiatry. 2007 Dec; 164(12): 1832–41.

3. Koenigsberg HW, Siever LJ, Lee H, Pizzarello S, New AS, Goodman M, Cheng H, Flory J, Prohovnik I. Neural correlates of emotion processing in borderline personality disorder.Psychiatry Res. 2009 Jun 30;172(3):192–9.

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