Borderline
Personality Disorder Research
Studies
|
|
Click
Here to see additional
clinical trials listed by NIMH. |
|
|
Researchers: Contact
info@neabpd.org
if you'd
like
to have your
BPD study
added to our website. |
|
Title: |
Treatment of Suicidal Behavior and
Self-Injury in BPD: Predictors of
Change |
|
Directed by: |
Barbara Stanley, Ph.D., Principal
Investigator |
|
Location: |
Columbia University and New York
State Psychiatric Institute
1051 Riverside Drive, Unit 42
New York, NY 10032 |
|
Approval / Funding: |
The study is approved by NYSPI
& Columbia University College of
Physicians & Surgeons IRB, Protocol
# 5752 |
|
Description: |
This study is a six month randomized
clinical trial of Dialectical
Behavior Therapy versus fluoxetine
medication with clinical management
for patients with BPD with a recent
history of suicidal or
self-injurious behavior |
|
Commitment: |
The study involves random assignment
into six months of treatment with
either a) Dialectical Behavior
Therapy or b) fluoxetine medication
with clinical management. An
additional 6 months of Dialectical
Behavioral Therapy is an option for
those who have been randomized into
the medication treatment condition.
It also includes several assessment
phases with several self-reports and
structured interviews prior to
beginning treatment (4-5 hours),
several follow up assessments (1
hour), a laboratory stress procedure
(1 hour), and two functional brain
imaging scans at the beginning and
end of the treatment phase (2-3
hours each). |
|
Criteria: |
Age 18 - 65, meets DSM-IV criteria
for BPD, history of at least one
suicide attempt, or one episode of
nonsuicidal self-injury, or a
hospitalization or ED visit for
suicidal ideation in the past six
months, with one additional episode
during the past year, current
suicidal ideation or urge to
self-injure, stable enough to be
treated on an outpatient basis and
washed out of any current
medications, not currently receiving
optimal care. |
|
Excluding Factors: |
No current substance
dependence, no current diagnosis of
bipolar I disorder or schizophrenia,
no metallic implants or pacemakers. |
|
Compensation: |
Up to $375 |
|
Contact: |
For more information, contact Amanda at 212-543-5747 |
|
|
|
|
|
|
|
Title: |
Study on Clinician and Researcher Perspectives on
Self-Injury |
|
Directed by: |
Alexander Chapman, PhD
Assistant Professor
Simon Fraser University
Department of Psychology
RCB5246, 8888 University Drive
Burnaby, BC, Canada V5A 1S6
PH 778-782-6932, FAX 778-782-3427
http://www.sfu.ca/psyc/faculty/chapman
http://www.dbtvancouver.com/ |
| Location: |
Online questionnaire. Link provided
after initial email communication. |
|
Description: |
I am currently conducting a study
examining clinician and researcher
perspectives on self-injury.
Specifically, I am interested in
examining the factors which may
prevent an individual from engaging
in self-injury over a period of
days, weeks or months. I am also
interested in how clinicians
conceptualize self-injury, and what
kinds of treatment strategies they
use to address this behaviour. As a
clinician, you have an important
role to play in understanding
barriers to self-injury, and I would
welcome your participation in this
study. |
|
Commitment: |
Participants will be asked to fill
out a brief set of online
questionnaires which ask about your
clinical training and education,
background and experience dealing
with self-injury, and how clients
you have seen have been able to
refrain from engaging in
self-injury. These questionnaires
should take no more than 30 minutes
of your time. Participation is
voluntary and confidential. |
|
Criteria: |
This study is open to researchers
and clinicians from all backgrounds
and countries. Given the nature of
some of the questions, we are
particularly interested in hearing
from individuals who assess or treat
patients who engage in self-injury
as part of their practice. |
|
Contact: |
Alexander L. Chapman, Ph.D., R.Psych.
chapman_lab@sfu.ca |
|
|
|
|
|
|
Title: |
Brain Imaging Study of Social
Perception in BPD |
|
Directed by: |
Eric A. Fertuck, Ph.D., Principal
Investigator |
| Location: |
Columbia University and New York
State Psychiatric Institute
Unit 42, Suite 2917
1051 Riverside Dr.
New York, NY 10032 |
|
Approval / Funding: |
The study is approved by NYSPI &
Columbia
University College of Physicians &
Surgeons IRB, Protocol # 5169 / NIMH
and Fund for Psychoanalytic Research |
| Description: |
We are investigating the neural
systems that are the bases of
interpersonal impairments in BPD by
having patients and controls
evaluate human faces and participate
in a social interaction game while
being scanned. The fMRI imaging is
considered a minimal risk and is
non- invasive. Participants get
compensated $500 for completing the
study and can obtain a copy of their
brain structural scan if interested. |
|
Commitment: |
The study involves an assessment
phase with several self-reports and
structured interviews (4-5 hours),
and a second functional brain
imaging phase on a separate day that
takes 2-3 more hours. |
|
Criteria: |
Female, age 18 - 45, DSM-IV criteria
for BPD, no current medication, or
on ineffective medication and
willing to taper (call for
clarification) |
|
Excluding Factors: |
No current substance dependence, no
current diagnosis of bipolar I
disorder or schizophrenia, no
metallic implants or pacemakers |
|
Compensation: |
$500 |
|
Contact: |
212 543-6544 |
|
|
|
|
|
|
Title: |
Emotion Regulation Skills Group |
|
Directed by: |
Kim L. Gratz, PhD
Principal Investigator |
| Location: |
University of Mississippi Medical
Center
2500 North State Street, Jackson, MS
39216
601-815-6450
EOE, M/F/D/V |
|
Approval / Funding: |
Not specified. |
| Description: |
If so, you may qualify for a
research study at the University of
Mississippi Medical Center on a new
group therapy for self-harm. This
study is being done to see if
teaching women new skills to manage
their emotions in healthy ways will
help them reduce their self-harm.
Participants will have 16 sessions
of group therapy and be asked to
complete interviews, questionnaires,
and a computer game several
different times. |
|
Commitment: |
Not specified. |
|
Criteria: |
Are you a woman who experiences
difficulties managing deliberate
self-harm? Would you like to reduce
your self-harm behavior? We are
currently seeking participants who
meet the criteria of self-harm
within the past year and currently
seeing an individual therapist or
case manager. |
|
Excluding Factors: |
No current substance dependence
No current diagnosis of bipolar I
disorder or schizophrenia |
|
Compensation: |
Group therapy will be provided at no
cost to study participants and
financial compensation is available. |
|
Contact: |
For further information about the
study, please contact us at
601-815-6344. All inquiries will be
kept strictly confidential. |
|
|
|
|
|
|
Title: |
Emotion Sensitivity Study |
|
Directed by: |
Professor Thomas Lynch, Principal
Investigator, and Dr Guy Mizon,
Research Fellow, Biobehavioural and
Virtual Reality Laboratory, Mood
Disorders Centre, School of
Psychology, University of Exeter,
Washington Singer Bldg, Perry Road,
Exeter, United Kingdom, EX4 4QG. |
| Location: |
School of Psychology
University of Exeter (UK) |
|
Approval / Funding: |
Not specified. |
| Description: |
This
study is being done to understand
factors that affect people’s
sensitivity to emotions (for
example, personality characteristics
and psychological symptoms), and how
emotions affect how people behave. |
|
Commitment: |
The study involves interview and
questionnaire measures, as well as
simple laboratory tasks. |
|
Criteria: |
We are currently seeking
participants living in the South
West of England who meet the
criteria of Diagnosis of Borderline
Personality Disorder and/or Major
Depressive Disorder. |
|
Excluding Factors: |
No current substance dependence
No current diagnosis of bipolar I
disorder or schizophrenia |
|
Compensation: |
Participants will be reimbursed with
up to £25 for their time and up to
£6 toward travel expenses. |
|
Contact: |
For further information about the
study, please contact us on 01392
264604. |
|
|
|
|
|
|
Title: |
Intranasal Oxytocin Challenge
Study in Borderline Personality
Disorder |
|
Directed by: |
Drs. Eric Hollander and Daphne
Simeon |
| Location: |
Mount Sinai School of Medicine
New York, NY |
|
Approval / Funding: |
This
study is MSSM IRB approved through
1/9/09, GCO#05-1271. |
| Description: |
Examines the effects of oxytocin on feelings of trust and
levels of stress in people with BPD.
Oxytocin is a stress hormone,
naturally found in the human brain
and is known to promote trust. |
|
Commitment: |
After a brief telephone screening
participants are paid for (1) an
initial intake interview with the
study psychiatrist, (2) Day 1 visit
to Mount Sinai's Clinic from
9am-1pm, during which participants
will receive a nasal spray of either oxytocin or placebo, complete
questionnaires and participate in
computerized tasks, (3) Day 2 visit
to Mount Sinai's Clinic from
9am-1pm, during which time
participants will receive a nasal
spray of either oxytocin or placebo,
complete questionnaires and
participate in computerized tasks. |
|
Criteria: |
Not specified. |
|
Excluding Factors: |
Not specified. |
|
Compensation: |
Not specified. |
|
Contact: |
For
more information about this study,
please contact Sarah at (212)
241-3089. |
|
|
|
| |
|
Title: |
Ziprasidone vs.
Placebo in Borderline Personality
Disorder |
|
Directed by: |
N/A |
| Location: |
Mount Sinai School of Medicine
New York, NY |
|
Approval / Funding: |
This study is MSSM IRB approved
through 11/20/08 and will be renewed
annually, GCO#06-1212. |
|
Description: |
Examines the effectiveness of ziprasidone
vs. placebo as treatment for BPD. |
|
Commitment: |
A 10-week program during which
participants are paid for (1) First
treatment visit which includes a
physical examination and EKG, (2)
Weekly visits for the initial 6
weeks of treatment consisting of 30
minute meetings with the study
psychiatrist to discuss their
symptoms, adjust the medication, and
fill out some questionnaires, and
(3) Bi-weekly visits for the last 4
weeks of treatment consisting of 30
minute meetings with the study
psychiatrist. |
|
Criteria: |
Participants must first complete the
Oxytocin Challenge Study. |
|
Excluding Factors: |
Not specified. |
|
Compensation: |
Not specified. |
|
Contact: |
For
more information about this study,
please contact Sarah at (212)
241-3089. |
|
|
|
|
|
|
Title: |
Intranasal Oxytocin
Treatment of Borderline Personality
Disorder |
|
Directed by: |
Not specified. |
| Location: |
Mount Sinai School of Medicine
New York, NY |
|
Approval / Funding: |
This
study is MSSM IRB approved through
8/13/09, GCO#07-0679. |
|
Description: |
Examines the effectiveness of daily
intranasal oxytocin, as compared to
placebo, in treating BPD. |
|
Commitment: |
This six-week treatment study.
Participants are paid for (1) Their
first treatment visit which includes
a physical examination, (2)
Bi-weekly visits during which
participants will meet with the
study psychiatrist to discuss their
symptoms, adjust the medication, and
fill out some questionnaires. |
|
Criteria: |
Participants must first complete the
Ziprasidone
Treatment Study |
|
Excluding Factors: |
Not specified. |
|
Compensation: |
Not specified. |
|
Contact: |
For
more information about this study,
please contact Sarah at (212)
241-3089. |
|
|
|
|
|
| Title: |
Not specified. |
|
Directed by: |
Not specified. |
| Location: |
Barnard College
New York City, NY |
|
Approval / Funding: |
Current IRB approval (#AAAB7625) is
valid until 11/17/08 and will be
renewed annually. |
|
Description: |
Psychologists at Barnard
College/Columbia University are
conducting a federally-funded
research study to understand the
daily experiences of people
suffering from Borderline
Personality Disorder in comparison
to other disorders. The research
study uses state-of-the-art
assessment methods focusing on the
relationship of personality
characteristics to moods, thoughts,
and particular symptoms. Note that
the study does not provide
treatment. |
|
Commitment: |
a) an initial interview in our lab
to determine eligibility, b) 2 more
lab visits to complete
questionnaires and computerized
tasks, and c) completing daily
questionnaires on a palm-pilot diary
for 3 weeks. |
|
Criteria: |
You are at least 18 years old, and
currently meet criteria for either
Borderline Personality Disorder, or
Avoidant Personality Disorder (a
severe form of Social Anxiety
Disorder/Social Phobia) or Major
Depressive Disorder (unipolar type) |
|
Excluding Factors: |
Not specified. |
|
Compensation: |
$230.00 (following pre-screening) |
|
Contact: |
For
info, call 212-854-4223 or e-mail
personality.studies@gmail.com. |
|
|
|
|
|
|
Title: |
Not specified. |
|
Directed by: |
Michael Suvak |
|
Location: |
Psychology Department
Boston University, Boston, MA |
|
Approval / Funding: |
NIMH |
|
Description: |
This study is designed to help learn
more about the way individuals with
borderline personality disorder
(BPD) experience emotions. |
|
Commitment: |
Not specified. |
|
Criteria: |
Participants should experience
characteristics of BPD (moodiness,
impulsivity, stormy/painful
relationships). |
|
Excluding Factors: |
Not specified |
|
Compensation: |
$40.00 |
|
Contact: |
Call (617)358-2247 or email Dr.
Suvak at
personalityandemotion@yahoo.com. |
|
|
|
|
|
